Viruses are the main enemies of the Dr. Mario games. They commonly appear in Red, Blue, and Yellow varieties, and they can be defeated only from using Megavitamins matching up three of the same colors. If the Megavitamins overflow the jar, thus plugging up the lid with their mass, the viruses believe that it is funny, at which point they start laughing. Viruses are Evil in alignment.
Viruses trace their origin to real-life germs, though real viruses are much more primitive, while the Mario series depicts the Viruses as somewhat proto-sentient, allowing them to coordinate attacks.
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The Viruses return in this game where they serve as the main enemies. Their designs in this game are completely different from most other games, as now they are completely legless, with just two arms coming from their sides. The red virus becomes a magenta virus (confusion), the blue one now becomes cyan (dizziness), while the yellow one just suffers design changes, inflicting "drowsiness".
The Viruses make a reappearance, this time wreaking havoc all across the Mushroom Kingdom with their powers, forcing Marioandhisfriends to team up with Bowser and his minions to bust the viruses. In addition to the standard red, yellow, and blue viruses, this game also has green, cyan, purple, and pink viruses.
Viruses are first seen in Mario & Luigi: Superstar Saga where they are only fought in Woohoo Hooniversity. In battle, they mainly attack by trying to bite either Mario or Luigi. If this attack isn't blocked back, the Virus may poison the brother. They are also defeated when all of the viruses in each battle is the same color. In the 3DS version, Viruses have Dr. Mario sound effects when this happens.
Viruses are fairly common in Mario & Luigi: Dream Team where they are seen only in the areas where Mario and Luigi are searching for the five pieces of the Ultibed, but can appear in Wiggly's area. The Viruses always fight in groups of 16 and they attack mainly by charging at Mario and Luigi. The way to defend against their charge varies depending on how it is done. If it involves the viruses charging in two lines, it must be jumped. If it has them run around the Bros. in a circle, it must be avoided by whacking them with the hammer, causing them to retreat. If three of the same colour are countered in a row, those viruses die instantly. They are defeated normally or by placing them in 3 same colors in a row, which can be done by attacking them, but not with counterattacks unlike in their Superstar Saga appearance.
Parentheses indicates statistics in Japanese version.
Numbers and words in gray indicate coding unavailable in normal gameplay.
Nomenclature[]
Viruses earned their name from the Latin Vīrus, a second declension noun meaning "poison". Other languages did not give the viruses alternative names, using the English voices as well, with the exception of the Japanese language, which calls them "Uirusu", which still means "Virus". Their names in other languages are as follows:
Latin: Vīrus (Declension as in Latin, but masculine, with the plural Vīrī (accusative Vīrōs) and the accusative singular Vīrum. Variable gender depending on the individual.)
• ⋆-Enemy, boss, or stat exclusive to the main game. • ⋆⋆-Enemy, boss, or stat exclusive to Minion Quest: The Search for Bowser. • ⋆⋆⋆-Enemy variants differ in Mario & Luigi: Superstar Saga + Bowser's Minions.